• Reorganization of the SARS-CoV-2 Spike protein

We are a theoretical biological physics research group, focusing on the dynamics of large-scale molecular assemblies, such as the ribosome, viral capsids and the SARS-CoV-2 Spike protein. Through the development and use of a variety of models, we are working to identify the physical principles that guide biomolecular dynamics. We are also interested in using molecular simulation approaches to interpret experimental data from a wide range of techniques, including biochemical, small-angle X-ray scattering and cryogenic electron microscopy. With the interdisciplinary nature of this research, we work closely with chemists, biologists, engineers, computational scientists and medical researchers, in order to obtain a comprehensive understanding that spans from the basic sciences to medical applications.