Magnetic nanoparticle-based microfluidic separation of circulating tumor cell populations enables understanding of the spreading of cancer and fosters development of various drug strategies. In this work we developed a microfluidic magnetic-activated cell sorting (MACS) system using a "bottom-up" approach employing both computational and experimental approaches to lead to optimized elements of device design.
Any opinions, findings and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation (NSF), Office of Naval Research (ONR), Department of Energy (DOE) or any other funding agency.
Plouffe, Brian D., Shashi K. Murthy, and Laura H. Lewis. "Fundamentals and application of magnetic particles in cell isolation and enrichment: a review." Reports on Progress in Physics 78, no. 1 (2014): 016601.