sysbioeng

Systems Bioengineering

Publications

Coming soon…

  • E. Dahlstorm and E. Levine, Dynamics of Heat-Shock Detection and Response in the intestine of Caenorhabditis elegans.
    K. S. Lee, D. Biron, and E. Levine, Roles of serotonin in the regulation of feeding revealed through mapping to a Brownian-like motion on the feeding-rate axis.
    Nowojewski, L. Lee, H. Voilquin and E. Levine, Pathogen avoidance by Caenorhabditis elegans is a pheromone-mediated collective behavior.
  • N. Peterman and E. Levine, Effects of temperature on specificity and efficiency of a bacterial regulatory RNA .
  • L. E. Lee, K. S Lee, J. Irazoquoi, and E. Levine, High-order organization of the C. elegans host response links glutamatergic neurotransmission and host tolerance of infection.

Quantitative and Physical Biology

  • K. S. Lee and E. Levine, Microfluidic platform for longitudinal imaging in C. elegans. JoVE, in press (2017). 
  • E. Korkmazhan, H. Teimouri, N. Peterman, and E. Levine, The dynamics of translation can determine the spatial organization of membrane-bound proteins and their mRNA. PNAS, 114 (51) 13424 (2017).
  • M. Scholtz, A. Diner, E. Levine, and D. Biron, Feeding dynamics are controlled by the need for energy and for information. PNAS 114(35), 9261–9266 (2017).
  • H. Teimouri, E. Korkmazhan, J. Stavans, and E. Levine, Sub-cellular mRNA localization modulates the regulation of gene expression by small RNAs in bacteria Phys Biol 14(5), 056001 (2017).
  • Bitran, W.Y. Chiang, E. Levine, and M. Prentiss, Mechanisms of fast and stringent search in homologous pairing of double-stranded DNA. PLoS Comput Biol Bio 13(3): e1005421 (2017).
  • K.S. Lee, S. Iwanir, R. Kopito, D. Biron and E. Levine, Regulation of food uptake by serotonin-dependent balance between two modes of feeding. Nature Comm 8, 14221 (2017).
  • K.S. Lee, L.E. Lee, and E. Levine, HandKAchip – Hands-free killing assay on a chip. Sci Rep 6 35862 (2016).
  • M. Scholz, D.J. Lynch, K.S Lee, E. Levine, D. Biron, A scalable method for automatically measuring pharyngeal pumping in C. elegans. J Neurosci Methods. S0165-0270 (2016).
  • Iwanir, A.S Brown A. Kazakov, K.S. Lee, A. Zaslaver, E. Levine and D. Biron, Serotonin promotes exploitation in complex environments by accelerating decision-making. BMC Biology 14 9 (2016).
  • N. Peterman and E. Levine, Sort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relations. BMC Genomics 17 206 (2016).
  • Neagu and E. Levine, A Primer on Quantitative Modeling, Methods Mol Biol. 1327 241 (2015).
  • H.-T Hsu,  H.-M.Chen, A. Burger, Z.Y. Yang, K. Zaret, T. Liu, E. Levine, and S.E. Mango, Recruitment of RNA Polymerase II by the pioneer transcription factor PHA-4, Science 348 1372 (2015).
  • S. Nagy, N. Tramm, J. Sanders, S. Iwanir, I. Shirley, E. Levine and D. Biron, Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms, eLife 3: e04380 (2014).
  • N. Peterman, A. Lavi-Itzkovitz and E. Levine, Large-scale mapping of sequence-function relations in small regulatory RNAs reveals plasticity and modularity, Nucl. Acids. Res. 42, 12177 (2014).
  • Obermayer and E. Levine, Inverse Ising inference with correlated samples, New Journal of Physics, 16, 123017 (2014).
  • Obermayer and E. Levine, Exploring the miRNA regulatory network using evolutionary correlations, PLoS Comput Biol 10, e1003860 (2014).
  • R. Kopito and E. Levine, Durable spatiotemporal surveillance of Caenorhabditis elegans response to environmental cues, Lab on Chip 21, 14 (2014).
  • Lavi-Itzkovitz, D. Jost, N. Peterman and E. Levine, Quantitative Effect of Target Translation on Small RNA Efficacy Reveals a Novel Mode of Interaction, Nucl. Acids. Res. 42, 12200 (2014).
  • Jost, A. Nowojewski, and E. Levine, Regulating the many to benefit the few: role of weak small RNA targets. Biophys. J. 104, 1773–1782. (2013)
  • H. Toledano, C. D’Alterio, E. Levine, and D.L. Jones. The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche. Nature 485(7400):605-10 (2012).
  • Levine, srRNAs, in Encyclopedia of Genetics, 2nd Ed. (Elsevir, Oxford 2012).
  • D. Jost, A. Nowokewski, and E. Levine, Small RNA Biology is Systems Biology. BMB Reports 44 ,11 (2011).