Our Lab

Biological Systems are Distributed, interacting, and complex. How do we understand them, manipulate them, control them?

Our lab combines modeling and computation, statistical and machine learning, and quantitative experiments in model systems, to study distributed biological systems, with a particular interest in gut-brain interactions

What we’re currently working on

Gut-brain interactions in stress response

Adaptation to complex environmental factors – including temperature, toxicity, and food availability – requires a coordinated response.

Gut-brain-immunity interactions

To combat pathogens in the environment and in the body, animals must coordinate an array of possible responses, from immunity to behavior.

Machine learning across biological scales

Concepts and tools from machine learning can help us understand how complex biological systems coordinate their actions.

Our microfluidics toolbox

HandKAChip allows multi-dimensional characterization of environmental response in individual animals and in groups.

WormSpa permits high-resolution longitudinal imaging of the dynamics of molecular and behavioral responses to precise perturbation.