This project aims to develop effective methods for early detection of cognitive changes. Using MRI, behavioral measures and our smartphone app, we will develop a computational model that can predict cognitive function from smartphone usage. Outcomes of this project may improve care and research for patients with cognitive impairments.

Background
Cognitive deficits associated with aging and neurodegenerative diseases pose major challenges to healthcare systems throughout the world. To facilitate successful aging, we need effective methods for early detection of neurodegeneration and for monitoring cognitive function. Recent advances in mobile health and artificial intelligence allow for inferring context information from smartphones. In this project, we will create a method for estimating cognitive changes from data collected passively from smartphone use. We will develop and evaluate the method by quantifying how accurately smartphone data predict cognitive changes estimated during lab tests and structural brain changes.

Study design
This is a longitudinal observational study that spans one year. Each participant will visit the lab 3 times: at the start of the study and after 6 and 12 months. During these sessions, we will acquire EEG recordings and participants will perform cognitive and motor tasks. During the first visit, our app will be installed on the participant’s phone. This app will collect phone use data such as what application was opened when, typing speed, time of calls, location information, mode of transportation, walking speed, device and screen status. It will also ask participants to answer very brief questions. To respect privacy, we do not collect data about what was typed on the phone, browsing or search history, received messages, audio, photos or video.

Interested in participating?
We are looking for right-handed volunteers 45-65 years of age, who own and regularly use an Android smartphone. Participants will spend ~8 hours in the lab across 3 visits and will be compensated for their time with up to $500 in gift cards. Sessions take place seven days per week in the Interdisciplinary Science & Engineering Complex (ISEC) of Northeastern University, located at 805 Columbus Ave in Boston. You can find more information about the FOCI research study here. If you are interested in participating, please fill out this online form. If you have questions, you can contact us at foci.study@gmail.com or 617-379-1112‬.

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