When do you need single-cell analysis?
At HUPO, I have been repeatedly asked: “Why analyze single cells when you can identify more peptides in bulk samples?”
Category Archives: Science
Direct causal mechanisms
Understanding biological systems: In search of direct causal mechanisms The advent of DNA-microarrays spurred a vigorous effort to reverse engineer …
Evaluating preprints
I am hugely enthusiastic for communicating research by preprints. So naturally, I am happy to see when the president and …
Single-cell analysis
The success of imaging technologies The molecular and functional differences among the cells making our bodies have been appreciated for …
Missed citations
I am sorry for not referencing your paper, but it would have undermined the novelty of our work. You know how Nature editors think.
Why I love preprints
The most frequent argument revolves around fear of losing priority of discovery. My usual question is: Have you ever felt that one of your peer reviewed papers is not cited and given credit when it should have been?
Single-cell proteomics
Ever since my lab posted the SCoPE-MS preprint, I have been repeatedly asked about the future potential and the cost …
Magnanimity pays off
Francis Crick exceeded the brilliance of his famous double helix model by this magnanimous act:
Premature human engineering
The news buzz alive with excitement about human genome editing, even human germline engineering. Successful germline engineering requires (1) a technology …
Deceptive Numbers
You want to estimate an important quantity. You compute an exact number purporting to estimate it. You compute another exact …
