Multimodal single-cell proteomics
The opportunities are beckoning. Which are likely to be most fruitful and impactful directions?
Author Archives: nslavov
Label-free single-cell proteomics
Recently, Matthias Mann and colleagues published a preprint (doi: 10.1101/2020.12.22.423933v1) reporting a label-free mass-spectrometry method for single-cell proteomics. Many colleagues …
My experience with elite journals
Over the last 15 years, my opinion about the significance of publishing in elite journals has evolved considerably. Below are some …
Promoting (your) research
“I am a scientist focused on conducting research, not on promoting it.” This thinking strongly resonated with me when I …
Bibliography for NIH proposals
NIH requires adding PMCID to references cited in proposals, and PMCID may be difficult to add because many reference libraries …
The cost of omics
Next generation DNA sequencing is ubiquitously integrated in modern biomedical research while mass-spectrometry proteomics remains less ubiquitous. In fact, mass-spectrometry …
Research success
We — the research community — can be much more successful if we invest more time and effort in what matters: Coming up with original new leads and helping each other grow as scientists and people. Happy and successful year to everybody!
The bigger picture
Why publishing a paper in a top journal maybe relatively unimportant ?
When do you need single-cell analysis?
At HUPO, I have been repeatedly asked: “Why analyze single cells when you can identify more peptides in bulk samples?”
Direct causal mechanisms
Understanding biological systems: In search of direct causal mechanisms The advent of DNA-microarrays spurred a vigorous effort to reverse engineer …
