Category Archives: Project 2 (Toxicology)

Trainee Spotlight – Anthony Su

Anthony Su is a Ph.D. candidate from the University of Michigan School of Public Health who has been studying Toxicology and working on PROTECT under Project 2 Leader Dr. Rita Loch-Caruso since 2016. In Rita’s lab, Anthony’s research seeks to understand the mechanisms of trichloroethylene (TCE) toxicity during pregnancy. When asked about the responsibilities within […]

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Project 2 Trainee Elana Elkin Receives the Karen Wetterhahn Memorial Award

PROTECT Project 2 Trainee Elana Elkin was recently granted the prestigious Karen Wetterhahn Memorial Award at the Annual NIEHS Superfund Research Program Meeting in Seattle on Nov. 19th. Elana received this award to honor her work examining how environmental contaminant exposure affects placental development and function. When asked about Elana’s work and progress on her […]

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PROTECT Undergraduate Research Fellow Tom Onsi wins poster award at UMICH Undergrad Research Opportunity Program Summer Research Symposium

On Wednesday July 31st, undergraduate M-Scholars Fellow Tom Onsi won a poster award at the 2019 University of Michigan Undergraduate Research Opportunity Program (UROP) Summer Research Symposium for his poster titled: “Extracellular vesicle production changes in response to toxicants in placental villous tissue”. This event is the culminating event for all University of Michigan students participating in […]

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PROTECT Trainees Max Aung and Amber Cathey present at the Society for Reproductive Investigation 66th Annual Scientific Meeting in Paris

Between March 12-16th, 2019, PROTECT Project 1 Trainees Max Aung and Amber Cathey attended the 66th Annual Scientific Meeting hosted by the Society for Reproductive Investigation in Paris, France. This year the meeting focused on a “From Innovation to Impact” theme and welcomed over 1,300 attendees, breaking the overall attendance record. [1] Max Aung presented […]

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Project 2’s Rita Loch-Caruso received the Mentorship Award at the 2019 Society of Toxicology Meeting

In March at the 2019 Society of Toxicology Annual Meeting Project 2 Leader Rita Loch-Caruso was presented with the Women in Toxicology Mentorship Award. From Saturday, March 9th to Thursday March 14th, PROTECT researchers attended the 58th Annual SOT Meeting in Baltimore, Maryland where Rita received this recognition after being secretly nominated by 22 of […]

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Trainee Spotlight: Elana Elkin

Elana Elkin is a PhD candidate from the University of Michigan working in the discipline of Toxicology under the mentorship of Project 2 Investigator Rita Loch-Caruso. Her dissertation is focused on her research as a PROTECT Trainee and is titled, First-Trimester Placental Cellular Responses to Trichloroethylene Metabolite S-(1, 2-Dichlorovinyl)-L-Cysteine Exposure. Elana has been a trainee […]

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PROTECT Project 2 Researchers receive awards, recognition, and praise at the Society of Toxicology Annual Meeting 2019.

From Saturday, March 9th to Thursday March 14th, PROTECT researchers attended the 58th Annual Society of Toxicology Meeting in Baltimore, Maryland. The Annual SOT Meeting has a global presence, consisting of “…members from 60+ countries and is dedicated to enhancing the impact and relevance of toxicology around the globe.”[1] When asked about the meeting PROTECT […]

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Trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine (DCVC) stimulates premature death in cell critical to placental development during the first-trimester of pregnancy

Today’s trainee spotlight was written by Elana Elkin on the publication “Trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine induces lipid peroxidation-associated apoptosis via the intrinsic and extrinsic apoptosis pathways in a first-trimester placental cell line.” Authors: Elana R. Elkin, Sean M. Harris, Rita Loch-Caruso Trichloroethylene (TCE) is a manmade chemical commonly used to clean grease off metal machine parts […]

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Project 2 Leader Loch-Caruso Cited in News Article Discussing EPA Review of 1,4-Dioxane and other Chemicals

On March 28, 2017, the University of Michigan hosted a panel of distinguished speakers who provided expert perspectives about changes made to the federal Toxic Substances Control Act (TSCA). They discussed the recent amendment to the law, The Frank R. Lautenberg Chemical Safety for the 21st Century Act (“Lautenberg Act”), which requires the Environmental Protection […]

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Trainee Elkin Presents on Award Winning Poster for NIEHS SRP Webinar

On March 27th, PROTECT Project 2 Trainee Elana Elkin  presented in a webinar hosted by the National Institute of Environmental Health Sciences (NIEHS) Superfund Research Program (SRP). The webinar was a part of an annual series which works to highlight the exceptional work of SRP trainee poster winners from their annual meetings. Elana Elkin’s poster, […]

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Trainee Elkin Wins First Place Prize for Poster Presented at the Annual SRP Meeting

On December 5th, a poster session was held during the Superfund Research Program (SRP) Annual Grantee Meeting in Durham, North Carolina. The session featured a competition for exemplary trainee posters in the categories of “environmental sciences and engineering” and “health sciences.” PROTECT trainee, Elana Elkin of Project 2, won first place in the health sciences […]

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Winners Selected for PROTECT Trainee Individual Development Plan Awards

Congratulations to our 2016 PROTECT Trainee Individual Development Plan (IDP) Award winners for their successful efforts in enhancing their extracurricular experiences and increasing their professional skills. Winners will be provided with a $1,500 stipend to be used towards attending a conference of their choice from a list of pre-approved options. The winners are:   Nerida […]

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PROTECT Identifies Biological Mechanisms Linking Exposure to Toxic Chemicals and Preterm Birth

Project 2 investigators are conducting innovative studies with human placenta and extraplacental membranes (which form the fetal compartment) to better understand the relationship between exposure to toxicants and preterm birth. Because immune cells such as macrophages can be important sources of reactive oxygen species as well as mediators of pro-inflammatory responses relevant to labor onset, […]

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PROTECT research findings suggest toxicant exposure may inhibit tissue resistance to microbial infections during pregnancy

PROTECT investigators are conducting innovative studies using in vitro models of human gestational tissues to better understand relationships between toxicant exposures and preterm birth. Microbial infection of the maternal reproductive tract is one of the most common known causes of preterm birth and pregnancy complications, yet the ability of toxicants to modify susceptibility to microbial infection […]

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Over 60 attend 5th annual PROTECT retreat in Dorado, Puerto Rico

On January 16th and 17th, PROTECT researchers, trainees, administrators, advisers, colleagues and guests gathered at the Embassy Suites Dorado del Mar in Dorado, Puerto Rico for the 5th annual PROTECT retreat to discuss research progress. This year’s theme focused on celebrating trainee achievements; over 20 trainees from across the five participating universities were in attendance. […]

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Congratulations to recent PROTECT graduates!

Ten PROTECT trainees recently graduated from their respective programs. We would like to congratulate them on their accomplishments, thank them for their service in PROTECT, and wish them well in the next step in their careers! Miguel Anzalota (Core C) completed his MPH degree at the University of Puerto Rico and recently started at the […]

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June 2014 Spotlight: PROTECT awarded five-year renewal grant

PROTECT has received a five-year, $13.5 million renewal award from the National Institutes of Health to continue its interdisciplinary investigation into the complex relationship between contamination and preterm birth. Click here to access the full article.

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PROTECT attends the SRP annual meeting

21 members of PROTECT (trainees, administrators and faculty) attended this year’s SRP meeting in Baton Rouge. In addition to presenting posters, PROTECT director Akram Alshawabkeh and trainee postdoc Kelly Hogan co-moderated the session on “Risks of Pollutants during Early Life Exposures”. Check out the pictures below from the meeting.

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Postdoc Kelly Hogan wins UMich Fellowship

Project 2 Postdoctoral Associate Kelly Hogan was awarded a two-year fellowship in the University of Michigan Postdoctoral Translational Scholars Program (PTSP), a program of the Michigan Institute for Clinical and Health Research.  All scholars are required to conduct a translational research program as part of their fellowship.  Congratulations Kelly!!

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PROTECT researcher at UMichigan awarded $1.4M grant from Preventing Preterm Birth Initiative

PROTECT researcher and University of Michigan professor Rita Loch-Caruso is part of a team at the University of Michigan that has earned $1.4 million in support from the Preventing Preterm Birth Initiative, part of the Bill & Melinda Gates Foundation’s Grand Challenges in Global Health, to study a leading cause of premature birth. For more […]

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Lauren Tetz presents at SRP Trainee Webinar Series 8/1 at 1pm

PROTECT Postdoc Lauren Tetz will be presenting as part of the SRP Trainee Webinar Series.  This is a series of webinars throughout the year highlighting the outstanding research/activities conducted by trainees (graduate students and post-docs).  Lauren’s presentation will be on August 1, 2012 at 1:00 p.m. Eastern Time and will include talks from Lauren Tetz […]

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PROTECT Grad Student Cassie Korte wins Poster Awards

Project 2 Graduate Student Cassie Korte (PhD Candidate, University of Michigan) won two poster awards this spring. The first presentation was awarded as part of the Society of Toxicology Reproductive and Developmental Toxicology Specialty Section at the Annual Society of Toxicology Meeting in March. Cassie’s poster won first place. The second presentation, “Oxidative insult activates […]

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PROTECT Trainee Cassie Korte wins poster award

PROTECT Project 2 Trainee Cassie Korte has won a poster award at the Graduate Academic Conference at Michigan State University

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PROTECT Trainee Lauren Tetz Defends Thesis

PROTECT Trainee (Project 2) Lauren Tetz successfully defended her thesis on April 16, 2012.  Our congratulations to the newly-minted Dr. Tetz!  Read more about her thesis topic below. MONO-2-ETHYLHEXYL PHTHALATE STIMULATES CELLULAR RESPONSES RELEVANT TO PARTURITION ABSTRACT: Diethylhexyl phthalate (DEHP) is an environmental pollutant used universally as a plasticizer in polyvinyl consumer products.  Exposure to DEHP increases […]

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PROTECT researcher links amniotic fluid to chemical exposure in fetuses

An article in Science of the Total Environment co-authored by Project 2 Leader Rita Loch-Caruso has described work by her and her colleagues showing that PBDEs (a chemical found in flame retardants and considered to hurt brain development) are present in amniotic fluid, which surrounds the fetus in the womb. While the study size was small […]

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PROTECT Researchers to Present at April 2 RiskeLearning Web Seminars

Project 2 Leader Rita Loch-Caruso and Project 1 Leader John Meeker presented an NIEHS SRP Risk e-Learning webinar in the series Early Life Exposures – Long-Term Health Consequences The session, which addressed PCE and Phthalates, was held on April 2, 2012. This session will feature SRP grantees Ann Aschengrau, Sc.D. (Boston University), John Meeker, Sc.D. (University of […]

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