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The Zhang Group

@ Northeastern University  

  • (Feb, 2016) Dr. Dali Wang from Shanghai Jiaotong University joins us as a postdoctoral fellow. Welcome Dali! We are glad to have you.
  • (Sep, 2015) Xueguang's second JACS paper, titled "Providing oligonucleotides with steric selectivity by brush-polymer-assisted compaction", has been published! Excellent work Xueguang!
  • (Aug, 2015) Our DFCI-NEU Cancer Grant with Prof. Jean Zhao at DFCI was successfully renewed!
  • (Apr, 2015) Xuyu’s paper on "Light-triggered, self-immolative nucleic acid-drug nanostructures" has been published in JACS, 2015, 137, 67122. Congrats Travis!
  • (May, 2015) Fei's manuscript on "Facile synthesis of nucleic acid-polymer amphiphiles and their self-assembly" has been accepted in ChemComm. (DOI: 10.1039/c5cc01934f). Congrats Fei!
  • (Jan, 2015) Prof. Zhang's proposal on "Supramolecular polycondensation of polymer brushes via DNA hybridization" won the NSF CAREER Award!
  • (Jul, 2014) Prof. Zhang and Prof. Zhao at Dana Farber won an award supported by NEU/DCFI to kickstart their joint project on anti-cancer nanoparticles!
  • (Jul 7, 2014) Xueguang's work on programmed assembly of polymer brushes titled "Polycondensation of polymer brushes via DNA hybridization" has been accepted in JACS (2014, 136 (29), pp 10214–10217). Congrats Xueguang!
  • Xuyu (Travis) Tan joined our lab. Big welcome!
  • (Sep 11, 2013) Prof. Zhang's paper, "Temperature-activated nucleic acid nanostructures", was published in JACS. (DOI: 10.1021/ja408465t)
  • ​(Apr 15, 2013) Our internal Tier 1 proposal with Dr. Yongmin Liu is funded! Thank you COS and COE for your belief in us!
  • (Apr 1, 2013) Dr. Hui Wang is joining the PNBL on April 1. Hopefully he is not fooling us!
  • Xueguang Lu, Yu Wang and Fei Jia are officially members of the PNBL. Welcome guys! Check out their awesome photos under "People"
  • (Mar 15, 2013) Prof. Zhang's co-authored paper, "Imaging mRNA expression levels in living cells with PNA·DNA binary FRET probes delivered by cationic shell-crosslinked nanoparticles," has been published in Org. Biomol. Chem. (doi:10.1039/C3OB26923J)
  • (Mar 14, 2013) Prof. Zhang's co-authored paper, "Effective protection and efficient delivery of siRNA by cationic shell-crosslinked knedel-like nanoparticles," has been published in Nuc. Acid Ther. (doi:10.1089/nat.2012.0390)
  • (Feb 18, 2013) Prof. Zhang's co-authored paper, "PEGylation of cationic, shell-crosslinked-knedel-like
  •  nanoparticles modulates inflammation and enhances cellular uptake in the lung," has been published online in Nanomedicine: NBM (
  • (Sep 28, 2012) Prof. Zhang's paper, "Antibody-Linked Spherical Nucleic Acids for Cellular Targeting," has been published online in J. Am. Chem. Soc. (doi:10.1021/ja306854d)
  • (Sep 27, 2012) Prof. Zhang's co-authored paper, "Imaging mRNA Expression in Live Cells via PNA-DNA Strand Displacement-Activated Probes," has been published in J. Nucleic Acids (doi:10.1155/2012/962652).
  • ​(August 29, 2012) The Polymer Nanobiotechnology Laboratory is now open for business! See HERE for the lab renovation log.

Department of Chemistry and Chemical Biology


Northeastern University


360 Huntington Avenue


Boston, MA 02115


​​Email: k.zhang (at) Office: 617-373-7089

Last Updated: Feb 2020