Our research aims to understand the mechanisms that regulate tissue regeneration. We primarily study the amazing regenerative abilities of the salamander, which are unique among vertebrate animals because they can regenerate large portions of organs including the limb, spinal cord, brain, eye, heart, liver, ovary, lung, and skin. Regeneration of these organs is no small feat considering a salamander’s limb can be 4cm long containing bone, muscle, nerves, and skin! The goal of this research is to use the knowledge gained from these remarkable animals to facilitate the discovery or implementation of regenerative medicine therapies.