Publications from Northeastern:

2023:

• Neuman KE, Zhang X, Mills C, Koppes R, Lewis LH, Koppes A. En route to next-generation nerve repair: static passive magnetostimulation modulates neurite outgrowth, Journal of Neural Engineering, 2023

2022:

• Bindas AJ, Nichols KN, Roth NJ, Brady R,  Koppes AN, Koppes RA. Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro, Scientific Reports, 2022
• Ghio C, Soukup JM, Dailey LA, Ghio AJ, Schreinemachers DM, Koppes RA, Koppes AN. Lactate production can function to increase human epithelial cell iron concentration, Cellular and Molecular Bioengineering, 2022
• Belanger K, Koppes AN, Koppes RA. Impact of Non-Muscle Cells on Excitation-Contraction Coupling in the Heart and the Importance of In Vitro Models, Advanced Biology, 2022
• Neuman KE, Kenny A, Shi L, Koppes AN, Koppes RA. Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering. Cells Tissues Organs, 2022
• Koppes AN, Koppes RA, Nichols KN. These organoids have some nerve: Uniting three germ layers in a human gastric model system. Cell Stem Cell, 2022

2021:

• Diaz D, Soucy JR, Lee A, Koppes RA, Koppes AN. Light irradiation of peripheral nerve cells: Wavelength impacts primary sensory neuron outgrowth in vitro. Elsevier BV, 2021
• Bindas AJ, Kulkarni S, Koppes RA, Koppes AN. Parkinson’s disease and the gut: Models of an emerging relationship. Acta Biomaterialia, 2021
• Winkelman MA, Koppes AN, Koppes RA, Dai G. Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells. APL Bioengineering, 2021
• Soucy JR, Burchett G, Brady R, Nichols K, Breault DT, Koppes AN, Koppes RA. Innervated adrenomedullary microphysiological system to model nicotine and opioid exposure. Organs-on-a-Chip, 2021
• Ghio C, Soukup JM, Dailey LA, Ghio AJ, Schreinemachers DM, Koppes RA, Koppes AN. Lactate production can function to increase human epithelial cell iron concentration. Preprint.

2020:

• Rogers ZJ, Zeevi MP, Koppes RA, Bencherif SA. Electroconductive hydrogels for tissue engineering: current status and future perspectives. Bioelectricity, 2020

• Soucy JR, Bindas AJ, Brady R, Torregrosa T, Denoncourt CM, Hosic S, Day G, Koppes AN, Koppes RA. Reconfigurable micro physiological systems for modeling innervation and multi-tissue interactions. Advanced Biosystems, 2020

• Ventre DM, Cluff A, Gagnon C, Diaz D, Koppes RA, Koppes AN. The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro. Journal of Neuroscience Research, 2020

• Hosic S, Bindas A, Puzan M, Lake W, Soucy J, Zhou F, Koppes RA, Breault D, Murthy S, Koppes AN. Rapid prototyping of multilayer micro physiological systems. ACS Biomaterials Science & Engineering, 2020

• Hosic, S., Lake, W., Stas, E., Koppes, R.A, Breault, D.T., Murthy, S.K., Koppes, A.N. Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury. Cellular and Molecular Bioengineering. 2020
• Nichols, K., Koppes, R.A., Koppes, A.N. Recent advancements in microphysiological systems for neural development and disease. Current Opinion in Biomedical Engineering. 2020
• Torregrosa, T., Webster, S., Aghaize, C., Soucy, J.R., Bertucci, C., Plant, L., Koppes, A.N., Koppes, R.A. Cyropreservation and functional analysis of cardiac autonomic neurons. Journal of Neuroscience Methods. 2020
• Snyder, J.,  Wang, C., Zhang, A., Li, Y., Luchan, J., Hosic, S., Koppes, R.A., Carrier, R.L., Koppes, A.N., Materials and Microenvironments for Engineering the Intestinal Epithelium. Biomaterials- Engineering Cell Behavior. 2020

2019:

• Soucy, J.R., Bindas, A.J., Koppes, A.N., Koppes, R.A. Instrumented microphysiological systems for real-time measurement and manipulation of cellular electrochemical processes. iScience. 2019
• Soucy, J.R., Askaryan, J., Diaz, D., Koppes, A.N., Annabi, N., Koppes, R.A. Glial cells influence cardiac permittivity as evidenced through in vitro and in silico models. Biofabrication. 2019.
• Spencer, A.R., Shirzaei Sani, E., Soucy, J.R., Corbet, C.C., Primbetova, A., Koppes, R.A., Annabi, N. Bioprinting of a cell-laden conductive hydrogel composite. ACS applied materials & interfaces. 2019.
• Bertucci, C., Koppes, R.A., Dumont, C., Koppes, A.N. Neural responses to electrical stimulation in 2D and 3D in vitro environments. Brain research bulletin. 2019.
• Ziemba, A.M., D’Amato, A.R., MacEwen, T.M., Puhl, D.L., Koppes, A.N., Koppes, R.A., Lennartz, M.R., Gilbert, R.J. Stabilized interleukin-4-loaded poly(lactic-co-glycolic) acid films shift proinflammatory macrophages toward a regenerative phenotype in vitro. ACS Applied Bio materials. 2019

2018:

• Soucy, J. R., Shirzaei Sani, E., Portillo Lara, R., Diaz, D., Dias, F., Weiss, A. S., Koppes, A. N., Koppes, R. A., Annabi, N. Photocrosslinkable Gelatin/Tropoelastin Hydrogel Adhesives for Peripheral Nerve Repair. Tissue Engineering Part A. 2018.
• Puzan, M.L., Legesse, B., Koppes, R.A., Fenniri, H., Koppes, A.N. Bioactive organic rosette nanotubes support sensory neurite outgrowth. ACS Biomaterials Science & Engineering. 2018.
• Spencer, A.R., Primbetova, A., Koppes, A.N., Koppes, R.A., Fenniri, H., Annabi, N. Electroconductive gelatin methacryloyl-PEDOT:PSS composite hydrogels: design, synthesis, and properties. ACS Biomaterials Science & Engineering. 2018

2016:

• Torregrosa, T. & Koppes, R. A. Bioelectric Medicine and Devices for the Treatment of Spinal Cord Injury. Cells Tissues Organs. 2016.
• Koppes, A.N., Keating, K.W., McGregor, A.L., Koppes, R.A., Kearns, K.R., Ziemba, A.M., McKay, C.A., Zuidema, J.M., Rivet, C.J., Gilbert, R.J., Thompson, D.M. Robust neurite extension following exogenous electrical stimulation within single walled carbon nano-tube composite hydrogels. Acta Biomaterialia., 2016.

2015:

• Anikeeva, P., Koppes, R. A. Restoring the sense of touch. Science. 2015.

Publications from Previous Institutions:

1. Koppes, R. A., Swank, D. M., Corr, D. A new experimental model for force enhancement: steady-state and transient observations of the Drosophila jump muscle. AJP Cell Physiol., 2015.
2. Park, S., Koppes, R. A., Froriep, U. P., Jia, X., Achyuta, A. K. H., McLaughlin, B. L., Anikeeva, P. Optogenetic control of nerve growth. Sci. Rep., 2015.
3. Canales, A., Jia, X., Froriep, U. P., Koppes, R. A., Tringides, C. M., Selvidge, J., Lu, C., Hao, C., Wei, L., Fink, Y., Anikeeva, P. Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo. Nat. Biotechnol., 2015. (Cover art below)
4. Lu, C., Froriep, U.P., Koppes, R.A., Canales, A., Caggiano, V., Selvidge, J., Bizzi, E., Anikeeva, P. Polymer Fiber Probes Enable Optical Control of Spinal Cord and Muscle Function In Vivo. Adv. Funct. Mater., 24, 6594, 2014. (Cover art below)
5. Koppes, R. A., Swank, D. M., Corr, D. A new experimental model to study force depression: The Drosophila jump muscle. J. Appl. Physiol., 2014.
6. Koppes, R. A., Herzog, W., Corr, D. T. Force enhancement in lengthening contractions of cat soles muscle in situ: transient and steady-state aspects. Physiol. Rep. 2013.
7. Schiele, N. R., Koppes, R. A., Chrisey, D. B., Corr, D.T. Engineering cellular fibers for musculoskeletal soft tissues using directed self-assembly. Tissue Eng. A. 2013.
8. Eldred, C. C., Simonov, D. R., Koppes, R. A., Yang, C., Corr, D. T., Swank, D. M., The mechanical properties of Drosophila jump muscle expressing wild-type and embryonic myosin isoforms. Biophys. J. 2010.
9. Schiele, N. R., Koppes, R. A., Corr, D. T., Ellison, K. S., Thompson, D. M., Ligen, L. A., Lippert, T. K., Chrisey, D. B. Laser direct writing of combinatorial libraries of idealized cellular constructs: Biomedical applications. Applied Surf. Sci. 2009.
10. Borotikar, B. S., Newcomer, R., Koppes, R. A., McLean, S. G. Combined effects of fatigue and decision making on female lower limb landing postures: Central and peripheral contributions to ACL injury risk. Clin. Biomech. 2008.