Publications

Preprint:

Praveen Kulkarni, Simone Grant, Thomas Morrison, Xuezhu Cai, Sade Iriah, Bruce Kristal, Jennifer Honeycutt, Heather Brenhouse, Jochen Hartner, Dan Madularu, Craig Ferris; Characterizing the human APOE epsilon 4 knock-in transgene in female and male rats with multimodal magnetic resonance imaging. DOI:10.21203/rs.3.rs-18040/v1; https://www.researchsquare.com/article/rs-18040/v1

Christopher M Lawson, Kilian FG Rentrup, Xuezhu Cai, Praveen P Kulkarni, Craig Ferris; Using multimodal MRI to investigate alterations in brain structure and function in rats with type 2 diabetes. DOI:10.21203/rs.3.rs-17165/v1; https://www.researchsquare.com/article/rs-17165/v1

Craig Ferris, Ju Qiao, Christopher M Lawson, Kilian FG Rentrup, Praveen Kulkarni; Evaluating blood-brain barrier permeability in a rat model of type 2 diabetes; DOI:10.21203/rs.3.rs-16970/v1; https://www.researchsquare.com/article/rs-16970/v1

2020

Benjamin C. Nephew, Alexandra Nemeth, Neelakshi Hudda, Gillian Beamer, Phyllis Mann, Jocelyn Petitto, Ryan Cali, Marcelo Febo, Praveen Kulkarni, Guillaume Poirier, Jean King, John L. Durant, Doug Brugge;  Traffic-related particulate matter affects behavior, inflammation, and neural integrity in a developmental rodent model. Environmental Research, Volume 183, 2020, https://doi.org/10.1016/j.envres.2020.109242

Xuezhu Cai, Ju Qiao, Praveen Kulkarni, Ian C. Harding, Eno Ebong, Craig F. Ferris; Imaging the effect of the circadian light–dark cycle on the glymphatic system in awake rats. Proceedings of the National Academy of Sciences Jan 2020, 117 (1) 668-676; https://doi.org/10.1073/pnas.1914017117

Honeycutt, J. A., Demaestri, C., Peterzell, S., Silveri, M. M., Cai, X., Kulkarni, P., Cunningham, M. G., Ferris, C. F., & Brenhouse, H. C. (2020). Altered corticolimbic connectivity reveals sex-specific adolescent outcomes in a rat model of early life adversity. eLife, 9, e52651. https://doi.org/10.7554/eLife.52651

Thomas R. Morrison, Praveen Kulkarni, Xuezhu Cai, Sade Iriah, Dipak Aggarwal, Shi-Fang Lu, Neal G. Simon, Dan Madularu, Craig F. Ferris; Treating head injury using a novel vasopressin 1a receptor antagonist. Neuroscience Letters, Volume 714, 2020, https://doi.org/10.1016/j.neulet.2019.134565

2019

Sumientra Rampersad, Biel Roig-Solvas, Mathew Yarossi, Praveen P. Kulkarni, Emiliano Santarnecchi, Alan D. Dorval, Dana H. Brooks; Prospects for transcranial temporal interference stimulation in humans: A computational study, NeuroImage, Volume 202, 2019, ISSN 1053-8119,  https://doi.org/10.1016/j.neuroimage.2019.116124

Ferris, C.F., Cai, X., Qiao, J. et al. Life without a brain: Neuroradiological and behavioral evidence of neuroplasticity necessary to sustain brain function in the face of severe hydrocephalus. Sci Rep 9, 16479 (2019). https://doi.org/10.1038/s41598-019-53042-3

Sunita Yadav, Grishma Pawar, Praveen Kulkarni, Craig Ferris and Mansoor Amiji;  CNS Delivery and Anti-Inflammatory Effects of Intranasally Administered Cyclosporine-A in Cationic Nanoformulations.  Journal of Pharmacology and Experimental Therapeutics September 1, 2019, 370 (3) 843-854; DOI: https://doi.org/10.1124/jpet.118.254672

Craig F. Ferris, Sarah Nodine, Trent Pottala, Xuezhu Cai, Tatiana M. Knox, Fanta H. Fofana, Soojin Kim, Praveen Kulkarni, Jonathon D. Crystal, Andrea G. Hohmann; Alterations in brain neurocircuitry following treatment with the chemotherapeutic agent paclitaxel in rats. Neurobiology of Pain, Volume 6, 2019, ISSN 2452-073X, https://doi.org/10.1016/j.ynpai.2019.100034.

Md Taufiq Nasseef, Jai Puneet Singh, Aliza T. Ehrlich, Michael McNicholas, Da Woon Park, Weiya Ma, Praveen Kulkarni, Brigitte L. Kieffer, and Emmanuel Darcq; Oxycodone-Mediated Activation of the Mu Opioid Receptor Reduces Whole Brain Functional Connectivity in Mice. ACS Pharmacology & Translational Science 2019 2 (4), 264-274 https://doi.org/10.1021/acsptsci.9b00021

Xuezhu Cai, Ju Qiao, Tatiana Knox, Sade Iriah, Praveen Kulkarni, Dan Madularu, Tom Morrison, Barbara Waszczak, Jochen C. Hartner, Craig F. Ferris. In search of early neuroradiological biomarkers for Parkinson’s Disease: Alterations in resting state functional connectivity and gray matter microarchitecture in PINK1 −/− rats, Brain Research, Volume 1706, 2019,  Pages 58-67, https://doi.org/10.1016/j.brainres.2018.10.033

Sade C. Iriah, Malav Trivedi, William Kenkel, Simone E. Grant, Kelsey Moore, Jason R. Yee, Dan Madularu, Praveen Kulkarni, Craig F. Ferris;  Oxycodone Exposure: A Magnetic Resonance Imaging Study in Response to Acute and Chronic Oxycodone Treatment in Rats. Neuroscience, Volume 398, 2019, Pages 88-101, https://doi.org/10.1016/j.neuroscience.2018.11.042

Jennifer A. Honeycutt, Camila Demaestri, Shayna Peterzell, Marisa M. Silveri, Xuezhu Cai, Praveen Kulkarni, Miles G. Cunningham, Craig F. Ferris and Heather C. Brenhouse; Too much, too young? Altered corticolimbic axonal innervation and resting state functional connectivity suggests sex-dependent outcomes in a rat model of early life adversity https://doi.org/10.1101/700666

Kulkarni Praveen, Morrison Thomas R., Cai Xuezhu, Iriah Sade, Simon Neal, Sabrick Julia, Neuroth Lucas, Ferris Craig F. Neuroradiological Changes Following Single or Repetitive Mild TBI. Frontiers in Systems Neuroscience, Vol 13, 2019, P 34, DOI=10.3389/fnsys.2019.00034 https://www.frontiersin.org/article/10.3389/fnsys.2019.00034

2018

Yadav S., Pawar G., Kulkarni P., Ferris C., Amiji M.; CNS Delivery and Anti-Inflammatory Effects of Intranasally-Administered Cyclosporine-A in Cationic Nanoemulsion Formulations. Accepted at Journal of Pharmacology and Experimental Therapeutics.

Kulkarni, P., Morrison, T.R., Cai, X., Iriah, S., Lange, M.S., Kennedy, L., Sabrick, J., Neuroth, L., Hoffman, G.E. and Ferris, C.F., 2018. A model of repetitive mild concussion with persistent brain injury but no symptomology-risk for Parkinson’s disease with aging?. bioRxiv, p.390856. https://doi.org/10.1101/390856

Cai, X., Qiao, J., Knox, T., Iriah, S., Kulkarni, P., Madularu, D., Morrison, T., Waszczak, B., Hartner, J.C. and Ferris, C.F., 2019. In search of early neuroradiological biomarkers for Parkinson’s Disease: Alterations in resting state functional connectivity and gray matter microarchitecture in PINK1−/− rats. Brain research1706, pp.58-67.  https://doi.org/10.1016/j.brainres.2018.10.033

Mitra, R., Qiao, J., Madhavan, S., O’Neil, G.L., Ritchie, B., Kulkarni, P., Sridhar, S., van de Ven, A.L., Kemmerling, E.M.C., Ferris, C. and Hamilton, J.A., 2018. The comparative effects of high fat diet or disturbed blood flow on glycocalyx integrity and vascular inflammation. Translational Medicine Communications3(1), p.10. https://doi.org/10.1186/s41231-018-0029-9

Sinkevicius, K.W., Morrison, T.R., Kulkarni, P., Cagliostro, M.K.C., Iriah, S., Malmberg, S., Sabrick, J., Honeycutt, J.A., Askew, K.L., Trivedi, M. and Ferris, C.F., 2018. RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory. Disease models & mechanisms, pp.dmm-032631. http://dmm.biologists.org/content/early/2018/05/10/dmm.032631

Iriah, S.C., Trivedi, M., Kenkel, W., Grant, S.E., Moore, K., Yee, J.R., Madularu, D., Kulkarni, P. and Ferris, C.F., 2018. Oxycodone Exposure: A Magnetic Resonance Imaging Study in Response to Acute and Chronic Oxycodone Treatment in Rats. Neuroscience.  https://doi.org/10.1016/j.neuroscience.2018.11.042

Upponi, J.R., Jerajani, K., Nagesha, D.K., Kulkarni, P., Sridhar, S., Ferris, C. and Torchilin, V.P., 2018. Polymeric micelles: Theranostic co-delivery system for poorly water-soluble drugs and contrast agents. Biomaterials170, pp.26-36. https://doi.org/10.1016/j.biomaterials.2018.03.054

Ferris, C.F., Morrison, T.R., Iriah, S., Malmberg, S., Kulkarni, P., Hartner, J.C. and Trivedi, M., 2018. Evidence of Neurobiological Changes in the Presymptomatic PINK1 Knockout Rat. Journal of Parkinson’s disease, (Preprint), pp.1-21. https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd171273

2017

Madularu, D., Yee, J. R., Kulkarni, P. and Ferris, C. F., System-specific activity in response to Δ9-tetrahydrocannabinol: A functional magnetic resonance imaging study in awake male rats. Eur J Neurosci. Accepted Author Manuscript. doi:10.1111/ejn.13754

Gharagouzloo, C.A., Timms, L., Qiao, J., Fang, Z., Nneji, J., Pandya, A., Kulkarni, P., van de Ven, A.L., Ferris, C. and Sridhar, S., 2017. Quantitative vascular neuroimaging of the rat brain using superparamagnetic nanoparticles: New insights on vascular organization and brain function. NeuroImage163, pp.24-33.

Ferris, C.F., Kulkarni, P., Yee, J.R., Nedelman, M. and de Jong, I.E., 2017. The Serotonin Receptor 6 Antagonist Idalopirdine and Acetylcholinesterase Inhibitor Donepezil Have Synergistic Effects on Brain Activity—A Functional MRI Study in the Awake Rat. Frontiers in Pharmacology8, p.279.

Dumais, K.M., Kulkarni, P.P., Ferris, C.F. and Veenema, A.H., 2017. Sex differences in neural activation following different routes of oxytocin administration in awake adult rats. Psychoneuroendocrinology81, pp.52-62.

Febo, M., Blum, K., Badgaiyan, R.D., Perez, P.D., Colon-Perez, L.M., Thanos, P.K., Ferris, C.F., Kulkarni, P., Giordano, J., Baron, D. and Gold, M.S., 2017. Enhanced functional connectivity and volume between cognitive and reward centers of naïve rodent brain produced by pro-dopaminergic agent KB220Z. PloS one12(4), p.e0174774.

Madularu, D., Kumaragamage, C., Mathieu, A.P., Kulkarni, P., Rajah, M.N., Gratton, A.P. and Near, J., 2017. A chronic in situ coil system adapted for intracerebral stimulation during MRI in rats. Journal of Neuroscience Methods284, pp.85-95.

2016

Moore, K., Madularu, D., Iriah, S., Yee, J.R., Kulkarni, P., Darcq, E., Kieffer, B.L. and Ferris, C.F., 2016. BOLD Imaging in Awake Wild-Type and Mu-Opioid Receptor Knock-Out Mice Reveals On-Target Activation Maps in Response to Oxycodone. Frontiers in neuroscience10.

Kenkel, W.M., Yee, J.R., Moore, K., Madularu, D., Kulkarni, P., Gamber, K., Nedelman, M. and Ferris, C.F., 2016. Functional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuit. Translational psychiatry6(3), p.e763.

Yee, J.R., Kenkel, W.M., Frijling, J.L., Dodhia, S., Onishi, K.G., Tovar, S., Saber, M.J., Lewis, G.F., Liu, W., Porges, S.W. and Carter, C.S., 2016. Oxytocin promotes functional coupling between paraventricular nucleus and both sympathetic and parasympathetic cardioregulatory nuclei. Hormones and behavior80, pp.82-91.

Kenkel, W.M. and Carter, C.S., 2016. Voluntary exercise facilitates pair-bonding in male prairie voles. Behavioural brain research296, pp.326-330.

Ganta, S., Singh, A., Rawal, Y., Cacaccio, J., Patel, N.R., Kulkarni, P., Ferris, C.F., Amiji, M.M. and Coleman, T.P., 2016. Formulation development of a novel targeted theranostic nanoemulsion of docetaxel to overcome multidrug resistance in ovarian cancer. Drug delivery23(3), pp.958-970.

Madularu, D., Kulkarni, P., Yee, J.R., Kenkel, W.M., Shams, W.M., Ferris, C.F. and Brake, W.G., 2016. High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats. Hormones and behavior82, pp.56-63.

de Jong, I., Herrik, K., Helboe, L., Foraster, M.A., Smagin, G., Leiser, S., Ferris, C. and Mørk, A., 2016. Idalopirdine, a 5-HT6 receptor antagonist in development for the treatment of mild-moderate Alzheimer’s disease: the scientific rationale. Neurobiology of Aging39, p.S12.

Yee, J.R., Kenkel, W.M., Kulkarni, P., Moore, K., Perkeybile, A.M., Toddes, S., Amacker, J.A., Carter, C.S. and Ferris, C.F., 2016. BOLD fMRI in awake prairie voles: A platform for translational social and affective neuroscience. NeuroImage138, pp.221-232.

Kenkel, W.M., Yee, J.R., Moore, K., Madularu, D., Kulkarni, P., Gamber, K., Nedelman, M. and Ferris, C.F., 2016. Functional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuit. Translational psychiatry6(3), p.e763.

2015

Ferris, C.F., Yee, J.R., Kenkel, W.M., Dumais, K.M., Moore, K., Veenema, A.H., Kulkarni, P., Perkybile, A.M. and Carter, C.S., 2015. Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats. Frontiers in behavioral neuroscience9.

Ganta, S., Singh, A., Kulkarni, P., Keeler, A.W., Piroyan, A., Sawant, R.R., Patel, N.R., Davis, B., Ferris, C., O’Neal, S. and Zamboni, W., 2015. EGFR targeted theranostic nanoemulsion for image-guided ovarian cancer therapy. Pharmaceutical research32(8), pp.2753-2763.

Kenkel, W.M., Yee, J.R., Porges, S.W., Ferris, C.F. and Carter, C.S., 2015. Cardioacceleration in alloparents in response to stimuli from prairie vole pups: the significance of thermoregulation. Behavioural brain research286, pp.71-79.

Madularu, D., Yee, J.R., Kenkel, W.M., Moore, K.A., Kulkarni, P., Shams, W.M., Ferris, C.F. and Brake, W.G., 2015. Integration of neural networks activated by amphetamine in females with different estrogen levels: A functional imaging study in awake rats. Psychoneuroendocrinology56, pp.200-212.

Kulkarni, P., Kenkel, W., Finklestein, S.P., Barchet, T.M., Ren, J., Davenport, M., Shenton, M.E., Kikinis, Z., Nedelman, M. and Ferris, C.F., 2015. Use of anisotropy, 3D segmented atlas, and computational analysis to identify gray matter subcortical lesions common to concussive injury from different sites on the cortex. PloS one10(5), p.e0125748.

Ferris, C.F., Yee, J.R., Kenkel, W.M., Dumais, K.M., Moore, K., Veenema, A.H., Kulkarni, P., Perkybile, A.M. and Carter, C.S., 2015. Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats. Frontiers in behavioral neuroscience9.

Madularu, D., Kulkarni, P., Ferris, C.F. and Brake, W.G., 2015. Changes in brain volume in response to estradiol levels, amphetamine sensitization and haloperidol treatment in awake female rats. Brain research1618, pp.100-110.

Yee, J.R., Kenkel, W., Caccaviello, J.C., Gamber, K., Simmons, P., Nedelman, M., Kulkarni, P. and Ferris, C.F., 2015. Identifying the integrated neural networks involved in capsaicin-induced pain using fMRI in awake TRPV1 knockout and wild-type rats. Frontiers in systems neuroscience9.

2014

Ferris, C.F., Kulkarni, P., Toddes, S., Yee, J., Kenkel, W. and Nedelman, M., 2014. Studies on the Q175 knock-in model of huntington’s disease using functional imaging in awake mice: evidence of olfactory dysfunction. Frontiers in neurology5.

Febo, M. and Ferris, C.F., 2014. Oxytocin and vasopressin modulation of the neural correlates of motivation and emotion: results from functional MRI studies in awake rats. Brain research1580, pp.8-21.

Jiang, J.K., McCoy, J.G., Shen, M., LeClair, C.A., Huang, W., Negri, A., Li, J., Blue, R., Harrington, A.W., Naini, S. and David, G., 2014. A novel class of ion displacement ligands as antagonists of the αIIbβ3 receptor that limit conformational reorganization of the receptor. Bioorganic & medicinal chemistry letters24(4), pp.1148-1153.

Ganta, S., Singh, A., Rawal, Y., Cacaccio, J., Patel, N.R., Kulkarni, P., Ferris, C.F., Amiji, M.M. and Coleman, T.P., 2016. Formulation development of a novel targeted theranostic nanoemulsion of docetaxel to overcome multidrug resistance in ovarian cancer. Drug delivery23(3), pp.958-970.

Shah, L., Kulkarni, P., Ferris, C. and Amiji, M.M., 2014. Analgesic efficacy and safety of DALDA peptide analog delivery to the brain using oil-in-water nanoemulsion formulation. Pharmaceutical research31(10), pp.2724-2734.

2013

Shamy, J.L., Kulkarni, P., Meadowcroft, M., Nedelman, M., Alberini, C., Ferris, C. and Baxter, M., 2013. Systemic administration of insulin-like growth factor 2 results in increased BOLD pharmacological MRI response in memory-related brain regions. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association9(4), pp.P159-P160.

2012

Kulkarni, P., Stolberg, T., Sullivanjr, J.M. and Ferris, C.F., 2012. Imaging evolutionarily conserved neural networks: preferential activation of the olfactory system by food-related odor. Behavioural brain research230(1), pp.201-207.

2010

Ferris, C.F. and Stolberg, T., 2010. Imaging the immediate non-genomic effects of stress hormone on brain activity. Psychoneuroendocrinology35(1), pp.5-14.

2009

Febo, M., Shields, J., Ferris, C.F. and King, J.A., 2009. Oxytocin modulates unconditioned fear response in lactating dams: an fMRI study. Brain research1302, pp.183-193.

Caffrey, M.K., Nephew, B.C. and Febo, M., 2010. Central vasopressin V1a receptors modulate neural processing in mothers facing intruder threat to pups. Neuropharmacology58(1), pp.107-116.

Febo, M., Akbarian, S., Schroeder, F.A. and Ferris, C.F., 2009. Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate. Neuroscience letters465(3), pp.267-271.

Nephew, B.C., Caffrey, M.K., Felix‐Ortiz, A.C., Ferris, C.F. and Febo, M., 2009. Blood oxygen level‐dependent signal responses in corticolimbic ‘emotions’ circuitry of lactating rats facing intruder threat to pups. European Journal of Neuroscience30(5), pp.934-945.

Luo, F., Schmidt, K.F., Fox, G.B. and Ferris, C.F., 2009. Differential responses in CBF and CBV to cocaine as measured by fMRI: implications for pharmacological MRI signals derived oxygen metabolism assessment. Journal of psychiatric research43(12), pp.1018-1024.

2008

Ferris, C.F., Stolberg, T., Kulkarni, P., Murugavel, M., Blanchard, R., Blanchard, D.C., Febo, M., Brevard, M. and Simon, N.G., 2008. Imaging the neural circuitry and chemical control of aggressive motivation. BMC neuroscience9(1), p.111.

Febo, M., Stolberg, T.L., Numan, M., Bridges, R.S., Kulkarni, P. and Ferris, C.F., 2008. Nursing stimulation is more than tactile sensation: it is a multisensory experience. Hormones and behavior54(2), pp.330-339.

Ferris, C.F., 2008. Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin. Progress in brain research170, pp.305-320.

2007

Luo, F., Li, Z., Treistman, S.N., Kim, Y.R., King, J.A., Fox, G.B. and Ferris, C.F., 2007. Confounding effects of volatile anesthesia on CBV assessment in rodent forebrain following ethanol challenge. Journal of Magnetic Resonance Imaging26(3), pp.557-563.

Febo, M. and Ferris, C.F., 2007. Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing. Neuroscience148(2), pp.400-412.

Henninger, N., Sicard, K.M., Li, Z., Kulkarni, P., Dützmann, S., Urbanek, C., Schwab, S. and Fisher, M., 2007. Differential recovery of behavioral status and brain function assessed with functional magnetic resonance imaging after mild traumatic brain injury in the rat. Critical care medicine35(11), pp.2607-2614.

Chen, W., Tenney, J., Kulkarni, P. and King, J.A., 2007. Imaging unconditioned fear response with manganese-enhanced MRI (MEMRI). Neuroimage37(1), pp.221-229.