
Congrats to Tim for getting Gold at the 5 minute Thesis Competition with a $200 cash prize! 🥇

Congratulations to Chenzhen Zhang on his Ph.D. Dissertaion: “Electrical Charging of Macromolecules for Targeted Delivery to Cartilage for Applications in Diagnostic Imaging and Drug Delivery”
Chenzhen has been an invaluable member of our lab, contributing towards many aspects of drug delivery and sharing his wide expertise to new lab members (AKA SuperChenny). We are so proud of you!
Our work demonstrates development of optimally charged cationic contrast agents for targeting negatively charged cartilage, enabling it for CT imaging. These contrast agents work at very low doses due to their charge based high intra-cartilage uptake. Great Work Chenzhen! Read it: Here
Our recently published article explores the use of combining IL-1Ra with cationic drug delivery carriers for post-traumatic osteoarthritis. The work demonstrates that electrically charged IL-1Ra is more effective than neutral IL-1Ra in repairing cartilage. It emphasizes the importance of creating a drug depot inside the cartilage for a sustained therapeutic effect. Congrats to Shikhar, Tim, Sumayyah, Tengfei, Chenzhen, and Armin! 50 days’ free access: Here