Peer-Reviewed Articles


157. Ganesh, S., Iyer, A.K., Weiler, J., Morrissey, D.V., Amiji, M.M., Combination of siRNA-directed Gene Silencing With Cisplatin Reverses Drug Resistance in Human Non-small Cell Lung Cancer, Mol. Ther. Nucleic Acids pubmed

156. Shah, L., Yadav, S., Amiji, M., Nanotechnology for CNS Delivery of Bio-Therapeutic Agents, Drug Deliv. Transl. Res. pubmed

155. Iyer, A.K., Singh, A., Ganta, S., Amiji, M.M., Role of integrated cancer nanomedicine in overcoming drug resistance, Adv. Drug Deliv. Rev. pubmed

154. das Neves, J., Araújo, F., Andrade, F., Michiels, J., Ariën, K.K., Vanham, G., Amiji, M., Bahia, M.F., Sarmento, B., In Vitro and Ex Vivo Evaluation of Polymeric Nanoparticles for Vaginal and Rectal Delivery of the Anti-HIV Drug Dapivirine, Mol Pharm. pubmed

153. Kalariya, M., Amiji, M.M., Systemically administered gp100 encoding DNA vaccine for melanoma using water-in-oil-in-water multiple emulsion delivery systems, Int. J. Pharm. pubmed

152. Talekar, M., Ganta, S., Amiji, M., Jamieson, S., Kendall, J., Denny, W.A., Garg, S., Development of PIK-75 nanosuspension formulation with enhanced delivery efficiency and cytotoxicity for targeted anti-cancer therapy, Int. J. Pharm. pubmed

151. Dehelean, C.A., Feflea, S., Gheorgheosu, D., Ganta, S., Cimpean, A.M., Muntean, D., Amiji, M.M., Anti-angiogenic and anti-cancer evaluation of betulin nanoemulsion in chicken chorioallantoic membrane and skin carcinoma in Balb/c mice, J. Biomed. Nanotechnol. pubmed

150. Xu, J., Gattacceca, F., Amiji, M., Biodistribution and pharmacokinetics of EGFR-targeted thiolated gelatin nanoparticles following systemic administration in pancreatic tumor-bearing mice, Mol. Pharm. pubmed

149. Deshpande, D., Janero, D.R., Amiji, M., Engineering of an ω-3 polyunsaturated fatty acid-containing nanoemulsion system for combination C6-ceramide and 17β-estradiol delivery and bioactivity in human vascular endothelial and smooth muscle cells, Nanomed: Therapeutics, Diagnostics, and Imaging pubmed

148. Ganesh, S., Iyer, A.K., Morrissey, D.V., Amiji, M.M., Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors, Biomaterials pubmed

147. Kriegel, C., Attarwala, H., Amiji, M., Multi-compartmental oral delivery systems for nucleic acid therapy in the gastrointestinal tract, Adv. Drug Deliv. Rev. pubmed


146. das Neves, J., Sarmento, B., Amiji, M., Bahia, M.F., Development and validation of a HPLC method for the assay of dapivirine in cell-based and tissue permeability experiments, J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pubmed

145. Kobayashi, E, Iyer, A.K., Hornicek, F.J., Amiji, M.M., Duan, Z., Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer: a pilot study, Clin. Orthop. Relat. Res. pubmed

144. das Neves, J., Rocha, C.M., Gonçalves, M.P., Carrier, R.L., Amiji, M., Bahia, M.F., Sarmento, B., Interactions of microbicide nanoparticles with a simulated vaginal fluid, Mol. Pharm. pubmed

143. Borcan, F., Soica, C.M., Ganta, S., Amiji, M.M., Dehelean, C.A., Munteanu, M.F., Synthesis and preliminary in vivo evaluations of polyurethane microstructures for transdermal drug delivery, Curr. Cent. J. pubmed

142. Kalariya, M., Ganta, S., Amiji, M. Multi-compartmental vaccine delivery system for enhanced immune response to gp100 peptide antigen in melanoma immunotherapy, Pharm. Res. pubmed

141. Min, C., Ohta, K., Kajiya, M., Zhu, T., Sharma, K., Shin, J., Mawardi, H., Howait, M., Hirschfeld, J., Bahammam, L., Ichimonji, I., Ganta, S., Amiji, M., Kawai, T., The antimicrobial activity of the appetite peptide hormone ghrelin, Peptides. pubmed

140. Iyer, A.K., He, J., Amiji, M. Image-guided nanosystems for targeted delivery in cancer therapy, Curr. Med. Chem. pubmed

139. Talekar, M., Ganta, S., Singh, A., Amiji, M., Kendall, J., Denny, W.A., Garg, S. Phosphatidylinositol 3-kinase inhibitor (PIK75) containing surface functionalized nanoemulsion for enhanced drug delivery, cytotoxicity and pro-apoptotic activity in Ovarian Cancer cells, Pharm. Res. [pubmed]

138. Fontana, C.R., Lerman, M.A., Patel, N., Grecco, C., de Souza Costa, C.A., Amiji, M.M., Bagnato, V.S., Soukos, N.S. Safety assessment of oral photodynamic therapy in rats, Lasers Med. Sci. [pubmed link]

137. Elangovan, S., Jain, S., Tsai, P.C., Margolis, H.C., Amiji, M. Nano-sized calcium phosphate particles for periodontal gene therapy. J. Periodontol. [pubmed link]

136. Attarwala, H., Amiji, M. Multi-compartment nanoparticles-in-emulsion formulation for macrophage-specific anti-inflammatory gene delivery, Pharm Res. [pubmed link]

135. Iftimia, N., Iyer, A.K., Hammer, D.X., Lue, N., Mujat, M., Pitman, M., Ferguson, R.D., Amiji, M. Fluorescence-guided optical coherence tomography imaging of colon cancer screening: a preliminary mouse study, Biomed. Opt. Express. [pubmed link]

134. Xu, J., Amiji, M. Therapeutic gene delivery and transfection in human pancreatic cancer cells using epidermal growth factor receptor-targeted gelatin nanoparticles, J. Vis. Exp. [pubmed link]

133. Jain, S. and Amiji, M. Tuftsin-Modified Alginate Nanoparticles as a NoncondensingMacrophage-Targeted DNA Delivery System, Biomacromolecules. [pubmed link]


132. Deshpande, D.D., Janero, D.R., Amiji, M.M. Therapeutic strategies for endothelial dysfunction, Expert Opin Biol Ther. [pubmed link]

131. das Neves, J., Michiels, J., Ariën, K.K., Vanham, G., Amiji, M., Bahia, M.F., Sarmento, B. Polymeric nanoparticles affect the intracellular delivery, antiretroviral activity and cytotoxicity of the microbicide drug candidate Dapivirine Pharm Res. [pubmed link]

130. Abeylath, S.C. and Amiji, M.M. “Click” synthesis of dextran macrostructures for combinatorial-designed self-assembled nanoparticles encapsulating diverse anticancer therapeutics. Bioorganic and Medicinal Chemistry, [pubmed link]

129. Jain, S., Attarwala, H., and Amiji, M. Non-condensing polymeric gene delivery systems: principles and application. Nano LIFE, [Invited review in the special thematic issue on “Nanomedicine: Therapeutics, Diagnostics, and Imaging” edited by Sofou, S. and Rege, K.]. (In press).

128. Klepac-Ceraj, V., Patel, N., Song, X., Holewa, C., Patel, C., Kent, R., Amiji, M.M., and Soukos, N.S. Photodynamic effects of methylene blue-loaded polymeric nanoparticles on dental plaque bacteria. Lasers in Surgery and Medicine, [pubmed link]

127. Milane, L., Duan, Z., and Amiji, M.M. Therapeutic efficacy and safety of combination paclitaxel/ lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant breast cancer. PLoS ONE. 6(9): e24075. (2011). [Publication link].

126. Abeylath, S.C., Ganta, S., Iyer, A., and Amiji, M. Combinatorial-designed multifunctional polymeric nanosystems for tumor-targeted therapeutic delivery. Accounts of Chemical Research, Published Online, DOI: 10.1021/ar2000106  (2011). [Pubmed link]

125. Xu, J., Ganesh, S., and Amiji, M. Non-condensing polymeric nanoparticles for targeted gene and siRNA delivery.International Journal of Pharmaceutics, [Invited review in the special thematic issue on “Non-Viral Gene Delivey” edited by Salem, A. and Burgess D.]. Published Online, DOI: 10.1016/j.ijpharm.2011.05.036  (2011). [Pubmed link]

124. das Neves, J., Bahia, M.F., Amiji, M., and Sarmento, B. Mucoadhesive nanomedicines: measurement and modulation of mucoadhesion at the nanoscale. Expert Opinion on Drug Delivery, Published Online, DOI: 10.1517/17425247.2011.586334 (2011). [Pubmed link]

123. das Neves, J., Amiji, M., and Sarmento, B. Mucoadhesive nanosystems for vaginal microbicide development: friend or foe?WIREs Nanomedicine and Nanobiotechnology, Published Online, DOI:10.1002/wnan.144 (2011). [Pubmed link]

122. Milane, L., Ganesh, S., Shah, S., Duan, Z., and Amiji, M. Multi-modal strategies for overcoming tumor drug resistance: hypoxia, Warburg’s effect, stem cells, and multifunctional nanotechnology. Journal of Controlled Release, Published Online, DOI:10.1016/j.jconrel.2011.03.032 (2011).

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121. Kriegel, C. and Amiji, M. Dual TNF-a/Cyclin D1 gene silencing using an oral microparticle system as a novel strategy for the treatment of inflammatory bowel disease. Clinical and Translational Gastroenterology, Published Online, DOI:10.1038/ctg.2011.1 (2011). [Journal link]

120. Milane, L., Duan, Z., and Amiji, M.M. Pharmacokinetic and biodistribution analysis of combination paclitaxel and lonidamine delivery in an orthotopic animal model of multi-drug resistant breast cancer using EGFR-targeted polymeric nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, Published Online, DOI: 10.1016/j.nano.2010.12.009 (2011). [Pubmed link]

119. Milane, L., Duan, Z., and Amiji, M.M. Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning. Cancer Cell International, 11:3 (2011). DOI:10.1186/1475-2867-11-3. [Pubmed link]

118. Dehelean, C.A., Feflea, S., Ganta, S., and Amiji, M.M. Anti-angiogenic effects of betulinic acid administered in nanoemulsion formulations using chorioallantoic membrane assay. Journal of Biomedical Nanotechnology, 7(2): 317-324 (2011). [Pubmed link]


For previous peer-reviewed publications, click this Pubmed link